I have obtained several directed insignts in biology through data science applied to genomics data. Here are a few representative publications.
- (with Stefan Feske) Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels. Nature Communications. Mar. 2019.
- (with Matija Snuderl) Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP containing the ancestral DUF1220 domain in pineoblastoma. Nature Communications. July. 2018.
- (with Orrin Devinsky) Cardiac Arrhythmia and Neuroexcitability Gene Mutations in resected brain tissue from patients with Sudden Unexpected Death in Epilepsy. Nature Genomic Medicine. Mar. 2018.
- (with Jason Huse) Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nature Communications. Mar. 2018.