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Kasthuri Kannan, PhD

I am an Associate Professor at The University of Texas MD Anderson Cancer Center. I am a computational data scientist with expertise in genomics (especially cancer), biomedical informatics and image processing. My several years of data-driven training include machine learning and statistics. Expert in analyzing large-scale data sets and mathematical modeling. Of late, my interest has converged on systems biology and spatial stochastic processes, namely, point processes and its aplication to multiplexed immunofluorescence images from cancer tissue biopsies.
My science interest is diverse and includes cancer biology, formal logic, physical theories, computing, and mathematics. My interest in biology and in particular cancer genomics has resulted in numerous publications.
Also, I am very passionate about teaching and have actively designed, developed and directed data science, machine learning and biomedical informatics courses. You can check out my lectures through the teaching links below.

Contact: kasthuri [at] gmail [dot] com

Research Publications CV Translational Pathology ITERT


  • PhD, Computer Science
    Texas A&M University, College Station
  • MS, Mathematics
    Texas A&M University, College Station
  • MSc, Mathematics
    Indian Institute of Technology, Chennai
  • BSc, Mathematics
    University of Madras, Chennai

Past Courses

Research Summary

I have obtained several directed insignts in biology through data science applied to genomics data. Here are a few representative publications.

Representative Publications
  • (with Stefan Feske) Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels. Nature Communications. Mar. 2019.
  • (with Matija Snuderl) Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP containing the ancestral DUF1220 domain in pineoblastoma. Nature Communications. July. 2018.
  • (with Orrin Devinsky) Cardiac Arrhythmia and Neuroexcitability Gene Mutations in resected brain tissue from patients with Sudden Unexpected Death in Epilepsy. Nature Genomic Medicine. Mar. 2018.
  • (with Jason Huse) Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nature Communications. Mar. 2018.
  • Dr. Adriana Heguy, PhD, Assistant Dean, Division of Advanced Research Technologies, NYU
  • Dr. Jason Huse, MD, PhD, Associate Professor & Director, MD Anderson Cancer Center
  • Dr. David Zagzag, MD, PhD, Chief, Neuropathology, NYU
  • Dr. Matthias Karajannis, MD, MS, Chief, Pediatric Neuro-Oncology, MSKCC
  • Dr. Matija Snuderl, MD, Director, Molecular Pathology, NYU
  • Dr. Orrin Devinsky, MD, Director, Comprehensive Epilepsy Center, NYU